Archivi: Seminars

Sustainability and the Future of Pharmaceutical Manufacturing

The talk will focus on the sustainability of the practice of new laboratory technologies, to ensure greener methods are beingapplied in science throughout and especially for the manufacturing of pharmaceuticals using Emerging Technologies (ET)such as Additive Manufacturing (AM) and Microfluidics, among others. Given the importance of climate change, and therelatively high impact that laboratories and… Leggi tutto »

Emerging Technologies for the manufacturing of safer and sustainable formulations

Novel biomaterials and manufacturing methods are emerging with potential to address the challenges associated with themanufacture of pharmaceuticals and drug delivery systems (DDSs) that will “teach new tricks to old drugs”, and on thedevelopment of personalized medicine and medical devices. Techniques such as 3D printing (3DP) have experienced asignificant price reduction making possible its use… Leggi tutto »

Polymeric nanoparticles for active targeting

Nowadays polymeric nanoparticles (NPs) appear as the most feasible and versatile delivery systems for targeted therapy. The presentation will address the surface decoration of NPs by a specific ligand, such as antibody, antibody fragment, and polysaccharide triggering an improved retention and accumulation of nanotherapeutics into the specific cells. Few examples of these concepts are provided… Leggi tutto »

Microfluidic Technology for the production of Solid Lipid Nanoparticles

Solid lipid nanoparticles (SLNs) have been explored as alternatives to colloidal drug delivery systems, such as lipid emulsions, liposomes and polymeric nanoparticles. They have many advantages over traditional drug delivery systems, they could prove to be an efficient delivery and targeting system for drug and biologically active molecules. Despite their extraordinary potential, translation from the… Leggi tutto »

Qualitative and quantitative analysis GMP-compliant of intact and digested proteins by LC-MS/MS: a Case Study

Over the past 10 years, there has been a remarkable increase in the use of LC-MS/MS for the qualitative and quantitativedetermination of proteins. So that now this technique can be considered an established bio-analytical platform for thequantification of macro molecular drugs and biomarkers. Moreover, with the extraordinary growth of therapeutic proteins in the pharmaceutical industry,… Leggi tutto »

Sustainability is in our DNA

The presentation illustrates the systematic approach that Vevy Europe applies to all new projects and the redesign of existingones in the environmental sustainability field. Methods and results obtained will be explained and commented upon.

Influence of Packing Fraction on Powder Permeability: A New Characterization Method

Many industrial applications, such as pharmaceutical, food, additive manufacturing processes, use powders. It is, therefore, very important to precisely characterize these materials to properly control and optimize the processes. Many are the factors affecting the macroscopic behavior of the powders: particle properties (e.g. size and shape distribution), cohesive forces, friction and interlocking between the particles,… Leggi tutto »